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Source: Clujul Medical.

Prostate cancer is a disease with major social and economic impact, therefore the development of minimally invasive therapeutic methods is highly important worldwide. Prostate crytherapy fulfills the requirements and was exten- sively developed in the USA. Material and method. We carried out a prospective study of patients with prostate adenocarcinoma, treated by US-guided transperineal primary prostate cryotherapy between October July at the Institute of Urology and Renal Transplantation of Cluj-Napoca and the Lukmed Urology Clinic.

Jun, Vol. Prostate cancer is a disease with major social and economic impact, therefore the development of minimally invasive therapeutic methods is highly important worldwide. Prostate crytherapy fulfills the requirements and was extensively developed in the USA. Material and method.

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We carried out a prospective study of patients with prostate adenocarcinoma, treated by US-guided transperineal primary prostate cryotherapy between October July at the Institute of Urology and Renal Transplantation of Cluj-Napoca and the Lukmed Urology Clinic.

Prostate cryoablation was performed using the Oncura Golden SeedNet 2 cryotherapy system, based on argon cooling and active heating with helium, and which may use up to 25 cryotherapy needles simultanoeusly and 5 temperature sensors. We assessed the early and late complications of this procedure.

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The patients in the study group were followed up for 12 to 54 months, mean period The patients' age ranged between 50 and 89 years, mean age The most frequent complications of cryotherapy were perineal echymosis Rectal or pelvic pain occurred in 9.

Erectile function one year after the operation was preserved in patients Severe complications rate was minimal one patient, representing 0.

There is a discrepancy in the Gleason score given on the initial biopsy and prostatectomy specimen, respectively, that affects both patients who can benefit from active surveillance and those who cannot benefit from curative surgical treatment, and for whom therapeutic alternatives must be established. In this context, our study aimed at analyzing the diagnostic concordance between biopsies and subsequent prostatectomies, in order to establish the accuracy of prostate biopsy in predicting final Gleason score of the prostatectomy specimens.

Urinary incontinence after 3 months was noted in only 2. Intestinal occlusion and hydronephrosis respectively were not reported in this group.

Prostate cryotherapy is a valid therapeutic option for prostate cancer; increasing the efficiency of the procedure will further reduce postoperative complications.

Moder cryotherapy equipment and use of fine cryotherapy needles IceRoadtogether with controlled freezing of the tumoral tissue, have opened a new prostate function in the treatment of prostate cancer, with minimal complications.

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